1,4-Dioxane Chronic Effects
EPA has not accustomed a Advertence Absorption (RfC) or a Advertence Dose (RfD) for 1,4-dioxane.
The California Environmental Protection Agency (CalEPA) has affected a abiding advertence acknowledgment akin of 3 milligrams per cubic beat (mg/m3) based on no furnishings on the liver, kidney, or claret in rats. The CalEPA advertence acknowledgment akin is a absorption at or beneath which adverse bloom furnishings are not acceptable to occur. It is not a absolute esimator of accident but rather a advertence point to barometer the abeyant effects. At exposures more greater than the advertence acknowledgment level, the abeyant for adverse bloom furnishings increases.