Purity: 95%~102% Application: An inhibitor of FRAP (mTOR) Storage: Store at -20° C Description:
Everolimus is a macrolide derived from Rapamycin (sc-3504) and shown to inhibit cell proliferation induced by growth factors. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Studies indicate that Everolimus is a FRAP (mTOR) inhibitor that displays high affinity toward the intracellular receptor FKBP12. Additionally, the Everolimus-FKBP12 complex decreases the activity of the S6K1 and 4EBP by binding to FRAP.
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